Quicksilver Scientific brings you a standardized, highly bioavailable form of cannabidiol (CBD), the non-psychogenic yet highly physiologically active compound derived from the hemp plant, Cannabis sativa. Cannabinoids, the family of compounds found in C. sativa, have been shown to have a broad influence on the body, impacting expression of more than 1000 genes. Among these genes, they have been shown to upregulate expression of cellular antioxidant defenses through pathways including Nrf2, a primary regulator of cellular antioxidant production, and downregulate that of many inflammatory signaling molecules.1
Cannabinoid receptors, namely CB1 and CB2, exist widely in the body, being highly expressed in the hippocampus and central nervous system (CNS), the immune system, and peripheral nervous system.2 Cannabinoid receptors are strongly stimulated by the endogenous compounds 2-arachidonoylglycerol and anandamide, the later whose name is taken from the Sanskrit word ananda, meaning joy or bliss.3 The immune system and nervous system produce endogenous cannabinoids which activate the CB1 and CB2 receptors.4 When taken orally, cannabinoids have an effect of increasing levels of the endogenous endocannabinoids and also bind these receptors.
Cannabinoids may act as neuroprotective antioxidants, with studies demonstrating an effect superior to alpha-tocopherol (vitamin E) and ascorbate (vitamin C) in preventing glutamate toxicity.* 5 Cannabinoids support a balanced mood and neurotransmitter balance, as well as modulate CNS excitability and the immune system response.* 4,6,7 They also support musculoskeletal system function and joint health.* 8,9